Ewa Niedzialkowska

Overview: I’m a biochemist with experience in structural biology. I use X-ray crystallography and cryo-EM in combinantion with biochemical and biophysical techniques to understand the relationship between structure and function of protein complexes.

Background? I studied biotechnology at the Jagiellonian University in Cracow, in Poland. I did my PhD as a joint project between University of Virginia and Jegillonian University, and studied potranslation modifications of chromatin during mitosis using X-ray crystallography. I did my first postdoctoral training at the Institute of Catalysis in Cracow, where I worked on structure-function relationship between proteins involved in opioid synthesis.The second postdoctoral training I did at the University of Virginia, where I studied cellular processes regulated by phase separation. In Ed Egelman’s lab my research focuses on actin and actin binding proteins.

Where do I see myself in 5 years? I would like to lead a research project in academic or industry setting.

Publications with our group (see more on Google Scholar)

Stabilization of F-actin by Salmonella effector SipA resembles the structural effects of inorganic phosphate and phalloidin. Ewa Niedzialkowska, Lucas A Runyan, Elena Kudryashova, Edward H Egelman, Dmitri S Kudryashov Published in Structure (London, England : 1993), March 2024 (see publication)

Stabilization of F-actin by Salmonella effector SipA resembles the structural effects of inorganic phosphate and phalloidin Ewa Niedzialkowska, Lucas A Runyan, Elena Kudryashova, Edward H Egelman, Dmitri S Kudryashov Published in bioRxiv : the preprint server for biology, January 2024 (see publication)