Photorhabdus luminescens TccC3 Toxin Targets the Dynamic Population of F-Actin and Impairs Cell Cortex Integrity.

Songyu Dong, Weili Zheng, Nicholas Pinkerton, Jacob Hansen, Svetlana B Tikunova, Jonathan P Davis, Sarah M Heissler, Elena Kudryashova, Edward H Egelman, Dmitri S Kudryashov


Due to its essential role in cellular processes, actin is a common target for bacterial toxins. One such toxin, TccC3, is an effector domain of the ABC-toxin produced by entomopathogenic bacteria of